QUANTITATION OF A NOVEL ENGINEERED ANTI-INFECTIVE HOST DEFENSE PEPTIDE, ARV-1502: PHARMACOKINETIC STUDY OF DIFFERENT DOSES IN RATS AND DOGS

Quantitation of a Novel Engineered Anti-infective Host Defense Peptide, ARV-1502: Pharmacokinetic Study of Different Doses in Rats and Dogs

The designer proline-rich antimicrobial peptide (PrAMP) Chex1-Arg20 amide (ARV-1502) is active against Gram-negative and Gram-positive pathogens in different murine infection models when administered parenterally and possesses a wide therapeutic index.Here we studied the pharmacokinetics of ARV-1502 for the first time when administered intramuscula

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Spatial Patterns of Travel Behavior in Rapidly Urbanizing Areas: A Case Study of Sango-Ota, Ogun State, Nigeria

Spatial interaction theory serves as a foundational framework for understanding the flow and patterns of transport movements within urban and rural areas.Hence, the objective of this paper was to evaluate the spatial patterns of travel behavior among residents in Sango-Ota, Ogun State, Nigeria, by assessing the factors influencing mobility, includi

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Trainability of Health-Related and Motor Performance Fitness in Adults with Cystic Fibrosis within a 12-Month Partially Supervised Exercise Program

Background.Regular physical activity plays an important role in the treatment of patients with cystic fibrosis (CF).This study is aimed at investigating the effects of a 12-month partially supervised exercise program on attributes of health-related and motor performance fitness, lung function (ppFEV1), BMI, and habitual physical activity (HPA, step

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